Lifestyle factors and lumbar disc disease: results of a German multi-center case-control study (EPILIFT)
نویسندگان
چکیده
INTRODUCTION In the large-scale case-control study EPILIFT, we investigated the dose-response relationship between lifestyle factors (weight, smoking amount, cumulative duration of different sports activities) and lumbar disc disease. METHODS In four German study regions (Frankfurt am Main, Freiburg, Halle/Saale, Regensburg), 564 male and female patients with lumbar disc herniation and 351 patients with lumbar disc narrowing (chondrosis) aged 25 to 70 years were prospectively recruited. From the regional population registers, 901 population control subjects were randomly selected. In a structured personal interview, we enquired as to body weight at different ages, body height, cumulative smoking amount and cumulative duration of different sports activities. Confounders were selected according to biological plausibility and to the change-in-estimate criterion. Adjusted, gender-stratified odds ratios with 95% confidence intervals were calculated using unconditional logistic regression analysis. RESULTS The results of this case-control study reveal a positive association between weight and lumbar disc herniation as well as lumbar disc narrowing among men and women. A medium amount of pack-years was associated with lumbar disc herniation and narrowing in men and women. A non-significantly lowered risk of lumbar disc disease was found in men with high levels of cumulative body building and strength training. CONCLUSIONS According to our multi-center case-control study, body weight might be related to lumbar disc herniation as well as to lumbar disc narrowing. Further research should clarify the potential protective role of body building or strength training on lumbar disc disease.
منابع مشابه
Cumulative occupational lumbar load and lumbar disc disease – results of a German multi-center case-control study (EPILIFT)
BACKGROUND The to date evidence for a dose-response relationship between physical workload and the development of lumbar disc diseases is limited. We therefore investigated the possible etiologic relevance of cumulative occupational lumbar load to lumbar disc diseases in a multi-center case-control study. METHODS In four study regions in Germany (Frankfurt/Main, Freiburg, Halle/Saale, Regensb...
متن کاملComparison the Recurrence Rate of Intervertebral Disc Herniation in Two Surgical Methods of Hemi laminectomy and Partial Laminectomy
Background & Aims: Between 5% and 15% of patients with low back pain suffer from lumbar disc herniation, so intervertebral disc disease is one of the most common causes of low back pain. Surgical intervention for lumbar disc herniation is recommended in patients with severe symptoms and has hopeful results. Although surgery can reduce pain and improve physical function in the short term, its lo...
متن کاملRelationship Between Lipid Profile and Cardiovascular Risk Factors and Lumbar Degenerative Disease in Adult Surgical Candidates
Background and Aim: There is no research consensus on the relationship between lipid profiles, atherosclerosis risk factors, and lumbar disc degeneration. The present study examined the relationship between lipid profile and some risk factors of cardiovascular diseases and lumbar disc degeneration in patients undergoing surgery. Methods and Materials/Patients: The study was conducted on ...
متن کاملمقایسه شیوه زندگی در زنان یائسه با دانسیته استخوانی طبیعی و غیر طبیعیدر بیمارستان شریعتی
Background & Objective: Osteoporosis is a serious public health concern known to have several etiologic factors. This study compared lifestyles among postmenopausal women with normal and abnormal bone marrow densitometries (BMD). Methods & Materials: In this case-control study, 81 postmenopausal women (33 cases with abnormal BMD and 48 control individuals with normal BMD) were selected using s...
متن کاملNeglected Alkaptonuric Patient Presenting with Steppage Gait
Even though intervertebral disc degeneration can be found in the natural course of alkaptonuria, detection of the disease by black disc color change in a patient without any other presentation of alkaptonuria is an exceptionally rare condition. We have reported a very rare case of alkaptonuria presented with low back pain and steppage gait in a 51-year-old male with a complaint of chronic low...
متن کامل